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Santiago de Cuba, capital of Cuba's southeastern Santiago de Cuba province, sits on a bay off the Caribbean Sea. Founded by the Spanish in 1515, it's known for colonial architecture and revolutionary history. The city's distinctive Afro-Cuban cultural influences are on display during July's Carnaval, a days-long festival with drum-beating parades featuring colorful costumes and son dancing, a precursor to salsa.
Santiago de Cuba is one of three cities (along with Havana and Cienfuegos) called on by Fathom's Adonia, the first U.S. cruise ship visiting Cuba.
Thanks to Cuba's relatively low traffic, and the compactness of the the city center, Santiago is easily walkable. Nevertheless, it can be quite hot (which is why you won't see many people out on the streets in the middle of the day), and the city is very hilly so stay hydrated, and don't overestimate your own energy levels.
Taxis can be easily found around most of the major plazas in the city.
Wikitravel contributed to this article.