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Cruise itinerary

4 night mediterranean

Ask your friends: Should I go?

Ship: MSC Orchestra (details)
Cruise line: MSC Cruises

Departure date: Saturday, April 25, 2026
Return date: Wednesday, April 29, 2026
Departure port: Valencia
Ports of call: Livorno, Civitavecchia
Return port: Genoa

Prices:

Balcony $472

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Suite $922

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Cruiseable's travel advisors can often find you additional savings & lower fares than the public prices listed here.

Day Location

1
Valencia
2
Valencia
3
Livorno
4
Civitavecchia
5
Genoa
6
Genoa

St. Lawrence Cathedral in Genoa, Italy.

A giant biosphere in the port of Genoa created by famed Italian architect Renzo Piano.

A shot of Palatine Hill in Rome. Legend says this is where Romulus killed his twin and founded Rome in 753 BC.

Trevi Fountain in Rome. Careful not to get hit by flying coins!

The elaborately painted blue ceiling of the Santa Maria Sopra Minerva in Rome.

Detail of the Colosseum in Rome, Italy.

Andrea Pozzo executed this vault fresco in Rome's Church of Sant'Ignazio in 1694 celebrating the success of the missionary activities of the Society of the Jesuits. (The light of the Gospel illuminating the four corners of the world.)

Sunset at the Spanish Steps (Scalinata della Trinità dei Monti) in Rome offers a perfect venue for people-watching. It's been a magnet for visitors since the 1700s.

Aisle leading up to the altar in St. Peter's Basilica in Vatican City.

Ostia Antica, a large archeological site, was once the main harbor of ancient Rome. Today it's near the modern suburb of Ostia, and you can wander through ruins of Roman streets and many buildings.

A color-enhanced view of the Colosseum in Rome at dusk.

The Colosseum in Rome was long the largest amphitheater in the word, holding 50,000 to 80,000 spectators who watched gladiatorial contests and public spectacles. It was built between 70 AD and 80 AD.

Looking down on the Ponte Sant'Angelo and the Tiber River from the top of Castel Sant'Angelo, Campo Marzio, Rome.

A panorama of the inside of St. Peter's Basilica in Vatican City.

Dusk approaches at La Taverna dei Mercanti restaurant in the Trastevere district of Rome.

Interior of St. Peter's Basilica, Vatican City.

The white marble Arch of Septimius Severus at the northwest corner of the Roman Forum in Rome was dedicated in AD 203 following a military victory.

Inside the Vatican Museum Library.

One of Rome's iconic sights, the 2,000-year-old Pantheon is the city's best-preserved ancient monument.

Michelangelo's masterpiece: The iconic ceiling of the Sistine Chapel in Vatican City.