MSC Opera has following cruise itineraries. Contact us for more information.

• 7 night mediterranean

  Starting in Greece with stops in Kotor, Dubrovnik, Genoa, Marseille, Málaga, Costa del Sol, Cadiz, Lisbon

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  2025 sails:

  Aug 22

  Aug 24

  Aug 29

  Aug 31

  Sep 05

  Sep 07

  Sep 12

  Sep 14

  Sep 19

  Sep 21

  Sep 26

  Sep 28

  Oct 03

  Oct 05

  Oct 10

  Oct 12

  Oct 17

  Oct 19

  2026 sails:

  May 13

  Oct 03

• 2 night mediterranean

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  2025 sails:

  Oct 31

• 4 night south africa

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  2025 sails:

  Nov 24

  Dec 01

  Dec 08

  Dec 15

  2026 sails:

  Jan 12

  Jan 19

  Jan 26

  Feb 02

  Feb 09

  Feb 16

  Feb 23

  Mar 02

  Mar 09

  Mar 16

  Mar 23

• 3 night south africa

  Starting in Cape Town

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  2025 sails:

  Nov 28

  Dec 12

  Dec 19

  2026 sails:

  Jan 16

  Jan 23

  Feb 13

  Mar 13

  Mar 20

  Mar 27

  Apr 14

• 5 night south africa

  Starting in Cape Town

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  2025 sails:

  Dec 22

  2026 sails:

  Apr 04

• 14 night south africa

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  2025 sails:

  Dec 27

• 26 night grand voyage

  Starting in Rhodes with stops in Genoa

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  2026 sails:

  Apr 17

• 10 night mediterranean

  Starting in Genoa with stops in Marseille, Málaga, Costa del Sol, Cadiz, Lisbon

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  2026 sails:

  May 13

  May 14

  May 16

  May 18

  May 20

  May 23

  May 24

  May 26

  May 28

  May 30

  Jun 02

  Jun 03

  Jun 05

  Jun 07

  Jun 09

  Jun 12

  Jun 13

  Jun 15

  Jun 17

  Jun 19

  Jun 22

  Jun 23

  Jun 25

  Jun 27

  Jun 29

  Jul 02

  Jul 03

  Jul 05

  Jul 07

  Jul 09

  Jul 12

  Jul 13

  Jul 15

  Jul 17

  Jul 19

  Jul 22

  Jul 29

  Aug 01

  Aug 02

  Aug 04

  Aug 06

  Aug 08

  Aug 11

  Aug 12

  Aug 14

  Aug 16

  Aug 18

  Aug 21

  Aug 22

  Aug 24

  Aug 26

  Aug 28

  Aug 31

  Sep 01

  Sep 03

  Sep 05

  Sep 07

  Sep 10

  Sep 11

  Sep 13

  Sep 15

  Sep 17

  Sep 20

  Sep 21

  Sep 23

  Sep 25

  Sep 27

  Sep 30

• 5 night mediterranean

  Starting in Genoa with stops in Marseille, Málaga, Costa del Sol, Cadiz, Lisbon

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  2026 sails:

  May 13

  Oct 05

• 1 night mediterranean

  Starting in Genoa with stops in Marseille

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  2026 sails:

  May 13

• 9 night mediterranean

  Starting in Marseille with stops in Málaga, Costa del Sol, Lisbon, Cadiz, Genoa

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  2026 sails:

  Oct 01

• 3 night mediterranean

  Starting in Genoa

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  2026 sails:

  Oct 07

• 18 night grand voyage

  Starting in Genoa with stops in Rome, Barcelona, Marseille, Gibraltar, St. Maarten/Saint Martin, Basse-Terre

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  2026 sails:

  Oct 29

• 3 night grand voyage

  Starting in Marseille with stops in Rome, Genoa

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  2026 sails:

  Oct 29

• 16 night grand voyage

  Starting in Barcelona with stops in Basse-Terre, Genoa, Marseille, Gibraltar, St. Maarten/Saint Martin

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  2026 sails:

  Oct 31

• 19 night grand voyage

  Starting in Basse-Terre with stops in Marseille, Barcelona, Gibraltar, Barbados, Catalina Island, St. Maarten/Saint Martin

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  2026 sails:

  Nov 01

• 15 night grand voyage

  Starting in Barcelona with stops in Basse-Terre, Gibraltar, St. Maarten/Saint Martin, Marseille

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  2026 sails:

  Nov 01

• 14 night grand voyage

  Starting in St. Maarten/Saint Martin with stops in Barcelona, Basse-Terre, Gibraltar

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  2026 sails:

  Nov 02

• 17 night grand voyage

  Starting in Barbados with stops in Barcelona, Gibraltar, St. Maarten/Saint Martin, Catalina Island, Basse-Terre

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  2026 sails:

  Nov 02

• 7 night southern caribbean

  Starting in Catalina Island with stops in Barbados, St. Maarten/Saint Martin, Basse-Terre, Curacao, Bonaire

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  2026 sails:

  Nov 16

  Nov 23

  Nov 30

  Dec 07

  Dec 14

  Dec 21

  Dec 28

  2027 sails:

  Jan 04

  Jan 11

  Jan 18

  Jan 25

  Feb 01

  Feb 08

  Feb 15

  Feb 22

  Mar 01

  Mar 08

  Mar 15

  Mar 22

  Mar 29

  Apr 05

  Apr 12

  Apr 16

  Apr 19

  Apr 23

  Apr 26

  Apr 30

  May 03

  May 07

  May 10

  May 14

  May 17

  May 21

  May 24

  May 28

  May 31

  Jun 04

  Jun 07

  Jun 11

  Jun 14

  Jun 18

  Jun 21

  Jun 25

  Jun 28

  Jul 02

  Jul 05

  Jul 09

  Jul 12

  Jul 16

  Jul 19

  Jul 23

  Jul 26

  Jul 30

  Aug 02

  Aug 06

  Aug 09

  Aug 13

  Aug 16

  Aug 20

  Aug 23

  Aug 27

  Aug 30

  Sep 03

  Sep 06

  Sep 10

  Sep 13

  Sep 17

  Sep 20

  Sep 24

  Sep 27

  Oct 01

  Oct 04

  Oct 08

  Oct 11

  Oct 15

  Oct 18

  Oct 22

  Oct 25

  Oct 29

• 14 night southern caribbean

  Starting in Barbados with stops in Catalina Island, Basse-Terre, St. Maarten/Saint Martin

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  2026 sails:

  Nov 19

  Nov 20

  Dec 03

  Dec 04

  Dec 17

  Dec 18

  Dec 31

  2027 sails:

  Jan 01

  Jan 14

  Jan 15

  Jan 28

  Jan 29

  Feb 11

  Feb 12

  Feb 25

  Feb 26

  Apr 15

  Apr 29

  May 13

  May 27

  Jun 10

  Jun 24

  Jul 08

  Jul 22

  Aug 05

  Aug 19

  Sep 02

  Sep 16

  Sep 30

  Oct 14

  Oct 28