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Cruise itinerary

21 night istanbul greek islands and mediterranean

Ask your friends: Should I go?

  • Departure date: Monday, September 14, 2026
  • Return date: Monday, October 05, 2026
  • Departure port: Civitavecchia
  • Ports of call: Marseille, Villefranche, Genoa, La Spezia, Cruising The Strait Of Messina, Rhodes, Kusadasi, Cruising The Dardanelles, Istanbul, Athens, Santorini, Katakolon
  • Return port: Civitavecchia

Prices:

  • Inside $3,399
  • Outside $3,669
  • Balcony $4,609
  • Suite $10,389

Cruiseable's travel advisors can often find you additional savings & lower fares than the public prices listed here.

Day Location
St. Lawrence Cathedral in Genoa, Italy.
The sugar cube houses of Oia perch atop red rock cliffs that loom over the Aegean Sea on the magical island of Santorini.
The interior of Hagia Sophia, built in 360 AD. It's now a museum called Ayasofya Müzesi, in Istanbul, Turkey.
Turkish pastries in Istanbul, Turkey.
National Archaeological Museum in Athens, Greece.
Walk on the narrow paths ringing the caldera of Santorini and you'll come across outcroppings of pumice — light and porous volcanic rock — that betrays the island's eruptive past.
Ölüdeniz is a beachfront village in Muğla Province on the Turquoise Coast of southwestern Turkey.
The iconic Sultanahmet Camii, or Blue Mosque, in Istanbul, Turkey.
The Gate of Salutation that leads to the Topaki Palace in Istanbul.
A giant biosphere in the port of Genoa created by famed Italian architect Renzo Piano.
The caldera of Santorini with a view of the whitewashed houses of Fira perched atop sheer cliffs that plunge a thousand feet to the sea. An ocean-filled volcanic ring was left behind by a titanic eruption 3,500 years ago that devastated the region. It's one of the most stunning views in the world.
The fortress Rumelihisarı in the Sarıyer district of Istanbul, Turkey.
An interior view of the Sultanahmet Camii, or Blue Mosque, in Istanbul, Turkey.
JD Lasica: "I still fondly recall the best lunch I ever had, from several years ago: fresh hand-picked grilled fish, horta, Greek salad and spectacularly awful homemade wine prepared by two lovely sister-owners of a taverna on the southeast side of Santorini who spoke not a word of English."
Agia Eirini church in Athens, Greece.
A color-enhanced view of the Colosseum in Rome at dusk.
The Basilica Cistern is the largest of several hundred ancient cisterns that lie beneath the city of Istanbul.
The Ortaköy Mosque at night in Istanbul.
A view of the interior cupola of Hagia Sophia, now a museum called Ayasofya Müzesi, in Istanbul, Turkey.
The Sultan Ahmed Mosque in Istanbul, Turkey, dates to 1616. It's popularly known as the Blue Mosque for the blue tiles decorating its inside walls. Visit it as part of a Mediterranean itinerary aboard Tere Moana.

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