American Serenade has following cruise itineraries. Contact us for more information.

• 8 night lower mississippi river and land tour

  Starting in New Orleans

  Select

  2024 sails:

  May 14

  May 21

  May 28

  Jun 04

  Jun 11

  Oct 08

  Nov 12

  2025 sails:

  Feb 14

  Feb 21

  Feb 28

  Mar 07

  Mar 14

  Mar 21

  Mar 28

  Apr 04

  Apr 11

  Apr 18

  Apr 25

  May 02

  May 09

  May 16

  May 23

  May 30

  Jun 06

  Aug 29

  Sep 05

  Sep 12

  Sep 19

  Sep 26

  Oct 03

  Oct 10

  Oct 16

  Oct 17

  Oct 23

  Oct 24

  Oct 31

  2026 sails:

  Feb 14

  Feb 21

  Feb 28

  Mar 07

  Mar 14

  Mar 21

  Mar 28

  Apr 04

  Apr 11

  Apr 18

  Apr 25

  May 02

  May 09

  May 16

  May 23

  May 30

  Jun 06

  Aug 29

  Sep 05

  Sep 12

  Sep 19

  Sep 26

  Oct 03

  Oct 10

  Oct 17

  Oct 24

  Oct 31

• 7 night lower mississippi river

  Starting in New Orleans

  Select

  2024 sails:

  May 27

  Jun 10

  Nov 04

  Nov 11

  Nov 25

  Dec 09

• 21 night complete mississippi river

  Starting in New Orleans

  Select

  2024 sails:

  Jun 17

  2025 sails:

  Jun 18

• 22 night complete mississippi river and land tour

  Starting in New Orleans

  Select

  2024 sails:

  Jun 18

  2025 sails:

  Jun 13

  2026 sails:

  Jun 13

• 22 night complete mississippi river experience and land tour

  Starting in New Orleans

  Select

  2024 sails:

  Jun 18

  2025 sails:

  Jun 13

• 8 night upper mississippi river and land tour

  Select

  2024 sails:

  Jul 09

  Jul 16

  Jul 23

  Jul 30

  Aug 06

  Aug 13

  Aug 20

  Aug 27

  Sep 03

  Sep 10

  2025 sails:

  Jul 04

  Jul 11

  Jul 18

  Jul 25

  Aug 01

  Aug 08

  Aug 22

  Aug 29

  Sep 05

  Sep 12

  Sep 19

  2026 sails:

  Jul 11

  Jul 25

  Aug 08

• 7 night upper mississippi river

  Select

  2024 sails:

  Jul 15

  Jul 29

  Aug 12

  Aug 26

  Sep 09

• 14 night grand heartland

  Starting in New Orleans

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  2024 sails:

  Sep 16

  2025 sails:

  Aug 20

• 15 night grand heartland and land tour

  Starting in New Orleans

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  2024 sails:

  Sep 17

  2025 sails:

  Aug 15

  Sep 26

  2026 sails:

  Aug 15

• 7 night historic mississippi river and land tour

  Starting in New Orleans

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  2024 sails:

  Oct 01

  Nov 19

  Nov 25

  Dec 01

  Dec 07

  2025 sails:

  Oct 30

  Nov 05

  Nov 07

  Nov 11

  Nov 13

  Nov 17

  Nov 19

  Nov 25

  Dec 01

  2026 sails:

  Nov 07

  Nov 13

  Nov 19

  Nov 25

  Dec 01

• 7 night music cities

  Select

  2024 sails:

  Oct 07

• 8 night music cities and land tour

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  2024 sails:

  Oct 15

  Nov 05

• 7 night the tennessee rivers

  Select

  2024 sails:

  Oct 21

• 8 night tennessee rivers and land tour

  Select

  2024 sails:

  Oct 22

  Oct 29

• 7 night upper mississippi river and land tour

  Select

  2026 sails:

  Jul 04

  Jul 18

  Aug 01