American Melody has following cruise itineraries. Contact us for more information.

• 7 night historic mississippi river and land tour

  Starting in New Orleans

  Select

  2025 sails:

  Mar 10

  Mar 16

  Mar 22

  Nov 28

  Dec 04

  Dec 10

  Dec 16

  2026 sails:

  Feb 16

  Feb 22

  Feb 28

  Mar 06

  Mar 12

  Nov 27

  Dec 09

  Dec 15

  Dec 21

  2027 sails:

  Feb 18

  Feb 24

  Mar 02

  Mar 08

  Mar 14

  Mar 20

  Nov 26

  Dec 02

  Dec 08

  Dec 14

• 8 night lower mississippi river and land tour

  Starting in New Orleans

  Select

  2025 sails:

  Mar 28

  Apr 04

  Apr 11

  Apr 18

  Apr 25

  May 02

  May 09

  Nov 07

  Nov 14

  Nov 21

  Dec 22

  Dec 29

  2026 sails:

  Apr 17

  Apr 24

  May 01

  May 08

  Nov 06

  Nov 13

  Nov 20

  2027 sails:

  Mar 26

  Apr 02

  Apr 09

  Apr 16

  Apr 23

  Apr 30

  May 07

  Nov 05

  Nov 12

  Nov 19

  Dec 27

• 22 night complete mississippi river experience and land tour

  Starting in New Orleans

  Select

  2025 sails:

  May 23

  2026 sails:

  May 22

  2027 sails:

  May 21

• 8 night ohio river

  Select

  2025 sails:

  Jul 04

  Jul 18

  Aug 01

  2027 sails:

  Jul 02

  Jul 16

  Jul 30

• 8 night ohio river and land tour

  Select

  2025 sails:

  Jul 11

  Jul 25

  Aug 08

  2027 sails:

  Jul 09

  Jul 23

  Aug 06

• 15 night grand ohio river

  Select

  2025 sails:

  Aug 15

  2026 sails:

  Jun 19

  Jul 04

  Aug 01

  Aug 15

• 8 night upper mississippi river and land tour

  Select

  2025 sails:

  Aug 29

  Sep 05

  Sep 12

  Sep 19

  Sep 26

  Oct 03

• 15 night grand heartland and land tour

  Starting in New Orleans

  Select

  2025 sails:

  Oct 17

  2026 sails:

  Oct 16

  2027 sails:

  Oct 15

• 11 night mississippi explorer and land tour

  Starting in New Orleans

  Select

  2026 sails:

  Mar 18

  Mar 28

  Apr 07

• 7 night upper mississippi river and land tour

  Select

  2026 sails:

  Jul 25

  Sep 05

  Sep 19

  Oct 03